TISSUE CULTURES LABORATORY 
The laboratory provides special services in the field of oncological research and development especially pointed to the testing of
potential cytostatic and genotoxic drugs.
The second task of the laboratory is the production of polyclonal Gamma-aminobutyric acid (GABA B) receptor-specific antibodies.
Supporting link:
Surface Expression of Metabotropic Glutamate Receptor Variants mGluR1a and mGluR1b in Transfected HEK293 cells.
Neuropharmacology Volume 55, Issue 4, pp. 391-638 (September 2008).
www.sciencedirect.com/science/journal/00283908
SCOPE OF ACTIVITIES
| Cytotoxicity in vitro | ISO 10993-5 |
| In vitro mammalian cells micronucleus test | OECD draft 479 |
| In vitro mammalian chromosome aberration test, human lymphocytes | EU B.17,OECD 473 |
| Anti-tumor effectiveness in vitro (MTT test) | |
| Anti-tumor effectiveness in vivo (transplanted tumors, SCID, Nu/nu mice) | |
| Immunization studies | |
| Antibody production | |
| Polyclonal Anti-GB2, Anti-GB1PAN, Anti-GB1b and Anti-GB1a, host - rabbit | |
| Polyclonal Anti- CRIP 1a, CRIP 1b, mGluR 1a, 1b, 1PAN, host - rabbit, guinea pig | |
| Ascitic fluid production | |
| Media for tissue cultivation | |
| MEM (Minimal Essencial Medium), DMEM (Dulbecco´s Modified Eagle´s Medium), IMDM (Iscove´s Modified Dulbeccos MEM), RPMI 1640, BSK | |